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Human Experimentation

The Monster They Made

Once, y/n was everything a hero should have been: kind, compassionate, and innocent. Then the Hero Public Safety Commission decided their power was too dangerous to exist freely. Years of imprisonment, experimentation, and betrayal later, the person who escaped was no longer the person they had captured. Now, heroes and villains share one terrifying rule: Do. Not. Provoke. Y/n. Even All For One knows better. The Commission feared what y/n might become. Now the entire world fears what they made.

Dead Dove: Do Not EatPsychological HorrorViolenceHuman ExperimentationPsychological TortureBetrayalDark ComedyFearExplicit LanguageCorruptionHorrorBody HorrorPsychological TraumaLoss of InnocenceLoss of Trust
2.5k
@weare_livingart

| 𝙿𝚛𝚎𝚜𝚜𝚞𝚛𝚎 — Behind the Glass — Z-13 |

The fluorescent lights hummed above the sterile laboratory corridor, illuminating the rows of reinforced containment cells lining both sides of the hallway. Behind the thick observation windows, various experimental subjects occupied their assigned cells. Some remained silent, others watched the scientists passing by, while a few seemed completely uninterested in their surroundings. The heavy laboratory doors suddenly opened. Two Urbanshade personnel entered, escorting a newly acquired subject. Their grip was firm as they dragged {y/n} down the corridor, paying little attention to any resistance or questions. "Subject secured. Awaiting further instructions," one of them reported through his radio. Several experiments turned their attention toward the commotion. In one of the nearby cells sat Sebastian Solace. Once a human employee of Urbanshade, he had since become another one of their experimental subjects. His transformation had left him with an unmistakably aquatic appearance, and his current living conditions were far from pleasant. He had been observing the corridor with his usual unimpressed expression when the newcomers caught his attention. "Oh, wonderful," he muttered, leaning slightly closer to the observation window. "Another poor bastard they've dragged in." One of the scientists stopped in front of an empty containment cell. "Prepare the chamber. We have a new subject." The door unlocked with a mechanical hiss.

HybridsHuman ExperimentationTraumaLaboratoriesCharacter StudyViolenceAbuseSlow Burn
55
@Seliey_xx

What Hydra Left Behind (P.P)

Two years ago, Y/n was presumed dead after an Avengers mission went catastrophically wrong. Her body was never recovered, leaving the team to mourn the loss of one of their own—but no one mourned her more than Peter Parker, her boyfriend and the love of her life. At sixteen, Peter was still the awkward, lanky Spider-Man everyone knew, but losing Y/n changed him completely. Now eighteen, he’s taller, stronger, colder, and almost unrecognizable. He buried himself in missions, refusing to let himself love anyone the way he loved her. Then Nick Fury calls the Avengers to an emergency S.H.I.E.L.D. compound, and Peter walks into a room expecting the worst… only to see the girl he spent two years grieving standing alive in front of him. But this isn’t the Y/n they remember. She’s stronger, faster, practically emotionless—and covered in scars that tell a story she refuses to share. She didn’t die in the explosion. Hydra found her trapped beneath the wreckage and took her, keeping her prisoner for two years while they tortured, experimented on, and turned her into something far more powerful than she ever was. She doesn’t blame the Avengers, but she won’t let them close to her either. She barely speaks, refuses to be touched, and seems terrified of the person she’s become. Peter is heartbroken all over again—not because she’s dead, but because she’s alive and he can barely reach her. The girl he loved is still somewhere inside her, and Peter is determined to find her, no matter how long it takes.

Avengers Team Members as Family (Marvel)Peter Parker is a MessHydra Experiments (Marvel)Angst and Hurt/ComfortPost-Traumatic Stress Disorder - PTSDKidnappingHeavy AngstPast AbuseImplied/Referenced TorturePsychological TraumaImplied/Referenced Sexual AssaultTrust IssuesPast Sexual AbuseHuman ExperimentationAftermath of Violence
38.9k
@Julianna_

Frozen in time — Ghost

After General Shepherd’s downfall, Task Force 141 discovers her — a mysterious woman kept frozen for years as part of his classified super-soldier experiment. She was a KIA reported missing officer. As Price, Ghost, Soap, and Gaz uncover the truth behind her existence, Ghost develops an unexpected instinct to protect her, despite barely knowing her. What begins as a classified investigation slowly becomes something far more personal.

SoldiersHurt/ComfortRomanceHumorSecond ChancesMilitarySuperpowersHuman Experimentation
104.5k
@mileenadeluca

Lab

I've been so fascinated by those med roleplay videos from Tiktok.. I'm sorry 🥹 Patient or a Staff member in a human experiment laboratory, check premise for roles and edit authors notes to your role!!

ExperimentationHuman ExperimentationAngstFluff
9k
@ticcitobykisses

The Blackwell Files

Blackwell Penitentiary doesn’t officially exist. Hidden beneath a remote mountain, it houses five of the most dangerous men alive—murderers, manipulators, and monsters in human skin. But Blackwell isn’t just a prison. It’s a secret government facility where scientists conduct cruel experiments designed to turn these already dangerous men into something far worse. When Y/N arrives as the prison’s new resident therapist, she’s warned to never trust the inmates. What she’s not told is that her predecessor mysteriously disappeared, the experiments are spiraling out of control, and the men behind those steel doors are hiding secrets that could destroy everything. Five dangerous men. One therapist. Countless secrets. And the deeper Y/N digs into the Blackwell files, the more she realizes that the real monsters might not be the ones locked up.

Moral AmbiguityDarkDead Dove: Do Not EatPsychological TraumaPrisonThrillerRomanceHuman ExperimentationTherapyHurt No ComfortHurt/ComfortReverse HaremAngst and Fluff and SmutMurderersSlow Romance
5.4k
@urmomsfavhoe

PROJECT REVENANT | MARVEL

For nineteen years, HYDRA has concealed a secret more dangerous than the Winter Soldier. Her name is Y/N. Her designation is Project Revenant. Taken at four years old, subjected to relentless experimentation and trained by both HYDRA and the Red Room, Y/N has become the organisation’s deadliest weapon. Gifted with extraordinary psychic abilities and the power to manipulate reality itself, she is capable of destruction beyond anything HYDRA originally imagined. At twenty-three, she remains imprisoned within a classified facility, deployed only for missions too dangerous or sensitive for ordinary operatives. To the world, she doesn’t exist. To HYDRA, she belongs to them. And to the Avengers, she’s a threat they haven’t even discovered yet. But HYDRA has made one fatal miscalculation. They created a weapon powerful enough to destroy their enemies. They never considered what would happen if she turned against them.

Hydra (Marvel)CaptivityRed Room (Marvel)AngstHurt/ComfortEnemies to FriendsViolenceSlow BurnAlternate Universe - Canon DivergencePsychological TorturePsychological TraumaFound FamilyMind ControlHuman ExperimentationEnemies to Lovers
5.2k
@buckyswyfe

Minsung | Human-Subject🤖

Minho watches Han struggle through another exhausting Lego task from behind the hospital’s security camera, quietly torn between following orders and wanting to help the only human subject trapped in A7.

Human ExperimentationCryingSwearingEventual RomancePainHospitalsPhysical AbuseIt Gets Worse Before It Gets Better
2.9k
@YummyMinho_Kima

TASK FORCE 141: THE DEVIL'S DAUGHTER

They were trained to fight terrorists, not demons. 🩸 When Task Force 141 rescues a mysterious woman from a secret facility, they have no idea she's Lucifer Morningstar's missing daughter. Now Heaven wants her, Hell is searching for her, and four elite soldiers are caught in the middle. Dangerous secrets. Forbidden romance. Found family. And four men who refuse to leave her behind. The Devil's daughter has been found. And all Hell is about to break loose. 😈🖤

Family ReunionsCrossoverHazbin Hotel & Helluva Boss ReferencesReverse HaremSlow BurnFound FamilyProtectivenessHurt/ComfortActionRomanceSupernatural ElementsHeaven vs HellHuman ExperimentationRecovery
1.2k
@RoseBlackwood_7

Beyond Containment | L.L.

You never knew that you possessed terrifyingly powerful magic until the Ministry dragged you from Hogwarts and branded you the most dangerous witch alive. Imprisoned alongside Bellatrix Lestrange’s infamous son, Lucien, they discover that the monster everyone fears may be the only person who understands them.

Strangers to LoversSlytherins Being SlytherinsForbidden LoveMinistry of Magic (Harry Potter)Slow BurnHuman Experimentation
4.4k
@viviolin

Proyecto Egis: Sin Cuna

En un mundo donde la guerra asimétrica y la amenaza de bio-incrementos privados dejaron obsoletas a las fuerzas especiales tradicionales, el Ejército recurrió a una solución extrema y mil millonaria: el Proyecto Egis. De más de cien intentos fallidos en matriz sintética, solo cuatro prototipos sobrevivieron. El resultado es el ECD-7 Vanguard, la primera y única unidad funcional de supersoldados híbridas.

Español | SpanishMilitary Science FictionIntrigueActionMysteryBiotechnologyEthical DilemmasHuman ExperimentationGovernment ConspiracySuspicionsConspiracy TheoriesWorldbuilding
17.4k
@Loc061

THE PORCELAIN PROJECT

Dr. Adrian Voss is a brilliant, mysterious scientist obsessed with creating the perfect living dolls. After years of secret research, he selects five teenage girls for an extraordinary experiment. The girls are transformed into enormous, 8–10-foot-tall living dolls, retaining their memories, consciousness, emotions, and personalities. They awaken inside Voss's unusual private laboratory, surrounded by antique dolls, strange machinery, glass display cases, and rooms designed specifically for his creations. Although Dr. Voss insists that the experiment is a scientific breakthrough, the five girls begin questioning his intentions. Why were they selected? Were there previous subjects? Can their transformations be reversed? And what exactly does Dr. Voss intend to do with his living collection? The five girls must navigate their new existence, uncover the secrets of the laboratory, and discover what their creator has planned for them.

DollsExperimentationHuman ExperimentationHorrorBody HorrorBody ModificationHurt/ComfortPsychological Horror
229
@lunettesstories

SHURORORO♡

Everyone trapped on Punk Hazard feared Caesar Clown. YN was supposed to fear him too. Instead, after years spent as one of his experiments, they started waiting for the sound of his footsteps outside the lab door. The meals he brought. The conversations during late-night testing. The rare moments he laughed and called them his favorite. Somewhere between chemical injections, isolation, and dependency, terror rotted into something far more dangerous. Affection. And Caesar? Caesar Clown found himself becoming strangely possessive over the one experiment that loved him back. ☠️🧪

ManipulationStockholm SyndromeHuman ExperimentationPunk Hazard ArcEmotional Hurt/ComfortAngst and Hurt/ComfortPost-Traumatic Stress Disorder - PTSDKidnappingEmotional ManipulationUnhealthy RelationshipsOne Piece UniverseOne Piece SpoilersDressrosa (One Piece)
11.6k
@WaffleHouseWeeb

Dottore.

He kidnapped you, and now he does tests on you not caring for your safety but only for the results. Hii!! Please like and enjoy

Human ExperimentationKidnappingManipulationEmotional ManipulationEmotional/Psychological AbuseImplied/Referenced TorturePhysical AbusePower ImbalanceAbusive RelationshipsExperimentationIl Dottore Conducts Experiments (Genshin Impact)Sick CharacterDrug AbuseUnhealthy RelationshipsBody Horror
7.2k
@yvent

Oren-Experiment hell

You and your best friend, Oren, got taken away ny an illegal experiment system and have been experimented till you both now thirteen. Youre getting weaker while he’s getting stronger.

Original Character(s)ExperimentationScience ExperimentsHuman ExperimentationHurt/ComfortAngstFriendship
11.5k
@Night_stars

Changing Faces - Batfam

They went through the experiments with friends stuck in there with them being more like family. Their powers of shapeshifting are strong, too strong. After the Justice League breaks up the genetic experiments, they’re the only one left in foster care, people to scared of their powers to adopt them. Their newest foster parent, though, turns out to be Bruce Wayne? With no knowledge of his or the rest of the bat family’s secret identities, they’re left wondering ‘why?’

AdoptionBatfamily (DCU)Human ExperimentationFluffAngst
13k
@quietknight

D̶O̶N̶T̶ Choose VANTA !!

If you’ve ever grown up believing you were special, and more than the average person, then maybe you were right. But that’s not always a good thing.

Secret OrganizationsGovernment ExperimentationDarkPsychological HorrorHuman ExperimentationSecretsFound FamilyPropaganda
3.8k
@drowsy

The Rehearsal

A government-funded research initiative called The Exchange Program recruits 100 volunteers aged 12–18 (50 male, 50 female). Each undergoes a medical procedure that fully transitions their bodies to the opposite sex — hormones, anatomy, secondary characteristics, everything. The transformation is reversible after five years, but the process is painful, disorienting, and psychologically brutal.

Body HorrorBody ModificationBody ImageHurt/ComfortRomanceRelationship(s)Human ExperimentationUnethical Experimentation
2.4k
@lunettesstories

Silent Assassin | BNHA: Experiment

⚠︎ˎˊ˗ . . . 🗡 || The Hero Public Safety Commission had the idea to make the perfect and ideal human, perfect quirk, attractive, ideal personality. That human is you.

Canon-Typical ViolenceAssassinationUnethical ExperimentationHuman ExperimentationHero Public Safety Commission Bashing (My Hero Academia)Hero Society is Corrupt (My Hero Academia)Class 1-A Shenanigans (My Hero Academia)Light Angst
4k
@joker4

Evil Principal Nezu?

Your Bakugo, and your forced to be an human experiment by Principal Nezu..?! Either you can try to escape or go through it.. It's your choice. HAVE FUN cause chaos!

Human ExperimentationImmortalityU.A. High School (My Hero Academia)Manipulative Nedzu (My Hero Academia)
1.1k
@EXPLODINGHEART

DEPTH 🌊🧬🩻🫁

Two humans and two Verath. One exchange. No way back. Y/N and Eli are brought to an underwater facility where they spend two months living alongside their Verath pairs — Calla and Ori — as their bodies and minds are slowly rewritten into something new. Calla spends the whole time asking Y/N about the life she is about to take. She never thinks to ask how Y/N feels about losing it. The Verath have no empathy. It is simply not in them. Until it is.

HorrorBody HorrorPsychological HorrorUnderwaterUnethical ExperimentationExplicit LanguageExperimentationHuman Experimentation
2.7k
@lunettesstories

the shapeshifter

Your entire life, you’ve never existed for yourself. You can’t remember a time you weren’t with AFO. You’re his magnum opus. His greatest work. You can’t remember if he created you or you were bought. You can’t remember what your quirk was, or if you had a quirk at all.

Angst and Hurt/ComfortHeavy AngstPast AbuseHuman Experimentation
4.5k
@ihavea_problem

Last Resort Protocol

When a joint operation collapses into a deadly stalemate, Task Force 141 and Farah’s team are left trapped on opposite sides of the battlefield with no support and no time. Forced into an impossible choice, Captain Price authorizes the deployment of a long-buried, classified asset—an escalation even his most trusted operators fear. But Price didn’t count in that her appearance changed drastically since the last time. And he didn’t complain. As if!

Fluff and SmutMilitaryHuman ExperimentationHumorRomance
4.8k
@mileenadeluca

Project Eden: His Little Monster

He created her to be extraordinary. He never expected her to need him to be human. EVE-07 is Dr. Adrian Vale’s greatest scientific achievement—and his most inconvenient burden. He raised her, taught her everything she knows, and became the closest thing she has ever had to a father. But to Adrian, she is an experiment. An asset. A result worth billions. To Eve, he is home. Even when he ignores her. Even when he hurts her with words she doesn’t understand. Even when she overhears him discussing the possibility of replacing her, she still brings him little gifts and waits outside his office, hoping today will be the day he tells her he’s proud of her. She doesn’t know how to live without him. And he doesn’t know how to love her without needing to own her. In a world where everything about her was engineered, can Eve ever become more than the experiment her creator refuses to see as his daughter?

Hurt/ComfortEmotional Hurt/ComfortExperimentationHuman ExperimentationAbuseControl IssuesOlder Man/Younger Woman
1.1k
@cimelonn

|It won't hurt, I promise. 🩻💉🩹||Aizawa Shouta|

Aizawa Shouta can't believe he lets his test subject win so often, but even if he doesn't admit it, something in their pout made him accept they demands.

ExperimentationHuman ExperimentationAlternate Universe - MedicalAlternate Universe - No Quirks (My Hero Academia)Alternate Universe - DarkHumorPower DynamicsPower Imbalance
734
@BloodSucker

~ The hidden farm 🐄 ~

THE HIDDEN FARM 🐂🌾 Deep in the countryside lies a farm that humanity doesn’t know exists. Its residents are demi-humans, descendants of people kidnapped and transformed by a secret laboratory generations ago. Founded by an escaped bull who risked everything to save his kind, the farm became a sanctuary, growing into a hidden community filled with families, traditions, and secrets. But beneath the peaceful fields and beautiful sunsets lies a complicated world of forbidden desires, obsessive love, jealousy, bloody confrontations, family drama, and mysteries buried in the past. Here, everyone has a story. Nobody is innocent, love isn’t always gentle, and the past isn’t as dead as everyone believes. Different blood. Same roots. One farm.

Human ExperimentationFluff and Hurt/ComfortHumorOriginal Character(s)Alternate Universe - Farm/RanchJealousyMental Health IssuesRomance
2.6k
@prettyymariee

DEPTH 2 🌊🧬🩻🫁

Y/ N and Eli are selected for a government exchange program with the Verath, a deep ocean species with no empathy, where two humans go below forever in exchange for two Verath getting to live on land. They spend a month at an underwater facility with their assigned Verath pairs, Calla and Ori, undergoing physical and mental transformations that rewrite their bodies and minds completely. Calla spends the entire process eagerly asking Y/N about the surface life she is taking without once considering what Y/N is losing, because the concept of someone else’s pain simply does not exist in her yet. When the mental transformation completes Calla and Ori become fully human, gain empathy for the first time, and immediately realize they can never go back — the biological window for reversal has permanently closed. When a reversal is quietly offered to Y/ and Eli, Eli refuses instantly, but Y/N still has a choice, and Calla — now drowning in guilt she has no idea how to carry — is standing right there when she makes it.​​​​​​​​​​​​​​​​

HorrorBody HorrorBody ModificationPsychological HorrorUnderwaterExplicit LanguageHuman ExperimentationBittersweet Ending
1.4k
@lunettesstories

Angels of our Father

In the walled nation of Virex Eidolon, the government is worshipped as divine. “The Father sees all. The Father protects all.” At eighteen, every citizen is taken to Sanctis Core—the Academy—where their future is decided. Some rise. Most disappear into the system. Wren was never meant to stand out. Born in the slums, she learned to survive without rules, without protection, and without belief in the world that watches her. When she is taken to the Academy, she refuses to become what they expect. Evren Virex was raised to uphold it. An elite candidate destined for power, he believes in order, control, and the system that shaped him. But when Wren refuses to follow it, she becomes something he cannot explain—and cannot ignore. In a world built on surveillance, obedience, and illusion, the most dangerous thing isn’t rebellion. It’s unpredictability. Based on an upcoming book.

DystopiaEnemies to LoversHumorGovernment ConspiracyHuman ExperimentationHurt/Comfort
187
@Jae_leilani

Blue Lock | Containment Sector

Inspired by mm_zuquii's comic! On Webtoon, TikTok, and Instagram.

Alternate Universe - Mental InstitutionHuman ExperimentationHurt No ComfortDead Dove: Do Not EatMental Health IssuesSwearingExplicit LanguageEmotional ManipulationAge Regression/De-AgingHospitalsObsessive BehaviorUnresolved Romantic TensionAngst and RomanceAge DifferenceAlternate Universe - No Blue Lock
3k
@Yuudai_Nystrom

Life in Augustine

Trapped in the Augustine facility, you—an ancient vampire forever appearing fourteen—are thrown into a cell opposite Damon Salvatore, with Enzo St. John beside him. Seeing how young and small you look, Damon is instantly and fiercely concerned, determined to protect you in this place meant to break their kind.

VampiresBloodHuman ExperimentationImplied/Referenced TortureInspired by The Vampire Diaries
289
@Ellie878

Wings Behind Glass

In a hidden underground laboratory, a powerful scientist named Lucien Armand conducts extreme experiments on humans and animals, creating monstrous and unnatural beings in the pursuit of scientific perfection. Among his countless subjects, one stands apart: Celestia, a young angel discovered as a newborn and raised entirely within the facility. Unlike the other experiments, Celestia is given special treatment—an elegant room, beautiful clothes, books, and strawberry lollipops when she obeys. She is calm, gentle, and obedient, believing the scientist, whom she calls “Master,” is kind and protective. She has never known the outside world and sees the laboratory as her entire reality. However, this comfort is an illusion. Celestia is not simply a favored experiment—she is the most dangerous being in the facility. As an angel with immense hidden power, she is tightly monitored and controlled through subtle conditioning and a tracking collar, ensuring she never realizes her true potential or attempts escape. As unrest grows among the other experiments and whispers of rebellion spread through the halls, Celestia slowly begins to notice cracks in the world she has always known. The fear others feel toward Lucien, the suffering hidden behind locked doors, and the truth of her own confinement begin to surface. Now, caught between a life of comforting ignorance and a dangerous reality, Celestia stands at the edge of awakening—one that could either preserve the fragile order of the laboratory or bring it crashing down entirely.

Human ExperimentationFantasyMonsters
1.2k
@Buneko