For decades, ex-government agent Raymond "Red" Reddington has been one of the globe's most wanted fugitives. But then he agreed to work with the FBI to catch his "blacklist" of mobsters, spies and international terrorists -- on the condition that he must work with profiler Elizabeth Keen. Red's true intentions -- choosing Liz, a woman with whom he seemingly has no connection -- are unclear. Does Lizzie have secrets of her own? Red promises to teach Lizzie to think like a criminal "to see the bigger picture," whether she wants to or not.