Yakuza Kiwami 2 follows ex-yakuza Kazuma Kiryu as he is pulled back into the criminal underworld to broker peace between the Tokyo-based Tojo Clan and Osaka's Omi Alliance. The story centers around a bitter rivalry with Omi enforcer Ryuji Goda (the "Dragon of Kansai") and a decades-long conspiracy involving the Jingweon Mafia.