The Road to El Dorado follows two clever con artists, Tulio and Miguel, who win a mysterious map to the legendary hidden city of gold, El Dorado. After accidentally ending up in the New World, they stumble across the hidden city and are mistaken for gods by its people. As they enjoy the luxury and wealth that come with their new status, they have to navigate suspicious priests, growing tensions, and their own friendship while deciding whether to exploit the city or protect it.